Isotope tracers in metabolic research : Principles and practice of kinetic analysis / Robert R. Wolfe, David L. Chinkes.

Rev. ed. of: Radioactive and stable isotope tracers in biomedicine / Robert R. Wolfe. c1992.

Includes bibliogr. references and index.

Basic characteristics of isotopic tracers -- Calculating specific activity and radiation dosages -- Calculation of substrate kinetics : single-pool model -- Calculation of substrate kinetics : multiple-pool model -- Mass spectrometry : instrumentation -- Determination of isotopic enrichment -- Measurement of substrate oxidation -- Measurement of total energy expenditure using the doubly-labeled water method -- Mass isotopomer distribution analysis -- Glucose metabolism -- Lipid kinetics -- Whole body protein synthesis and breakdown -- Measurement of the synthesis of specific proteins -- Measurement of regional or tissue protein breakdown -- Arterial-venous balance technique to measure amino acid kinetics -- Nuclear magnetic resonance.