Learning what works : infrastructure required for comparative effectiveness research : workshop summary / by LeighAnne Olsen; Claudia Grossmann; J Michael McGinnis; Institute of Medicine (U.S.). Roundtable on Value & Science-Driven Health Care.

The need and potential returns for comparative effectiveness research -- The work required -- The information networks required -- The talent required -- Implementation priorities -- Moving forward -- Appendixes -- Learning what works best: the nation's need for evidence on comparative effectiveness in health care -- Comparative effectiveness studies inventory project -- Comparative effectiveness research priorities: IOM recommendations (2009) -- Comparative effectiveness research priorities; FCCCER recommendations (2009) -- Affordable Care Act (ACA) (2010) provisions for the Patient-Centered Outcomes Research Institute (PCORI) -- Workshop agenda -- Biographical sketches of workshop participants -- Workshop attendee list

"It is essential for patients and clinicians to have the resources needed to make informed, collaborative care decisions. Despite this need, only a small fraction of health-related expenditures in the United States have been devoted to comparative effectiveness research (CER). To improve the effectiveness and value of the care delivered, the nation needs to build its capacity for ongoing study and monitoring of the relative effectiveness of clinical interventions and care processes through expanded trials and studies, systematic reviews, innovative research strategies, and clinical registries, as well as improving its ability to apply what is learned from such study through the translation and provision of information and decision support etc.